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Pfizer says it exceeded the acceptable daily intake level of a cancer-causing compound in those batches, recalling some shipments of the blood pressure drug Accuretic as well as authorized generic versions of the drug.

The compound in the drug is nitrosamine, which is found in water and beer, as well as some foods such as bacon and grilled meat. It is believed to pose a small risk of cancer in patients who use the drugs for a long time.

Such recalls have become commonplace in recent years, as private labs and companies detect cancer-causing foreign substances and initiate large-scale recalls, particularly of blood pressure medications. In September 2020, the Food and Drug Administration, companies to call them compounds a regularly. The agency announced another nitrosamine-related recall on Wednesday. a Sandoz drug means reducing the discomfort associated with painful musculoskeletal conditions.

FDA in 2018 announced the recall Drugs containing valsartan were discovered after NDMA, a possible carcinogen.

A wave of recalls occurred after Valisure, a pharmacy company that regularly tests the drug for impurities, stated that nitrosamine was found in ranitidine. heartburn medicine Zantac. validation petitioned the FDA To expand testing after ranitidine was found to have a type of nitrosamine called N-nitrosodimethylamine or NDMA, which is considered a possible carcinogen.

drugs such as metforminfor people with diabetes and chantixThey have also faced recalls regarding possible carcinogens for those trying to quit smoking.

Accuretic has relatively few users: it received around 1,300 in 2020. According to data from IQVIA, an analytics company, its generic formulation has about 192,000 users. The generic drug consists of the ingredients quinapril and hydrochlorothiazide and generated sales of approximately $4.7 million in 2020, according to IQVIA data.

Pfizer said in a press release that it was not aware of any adverse events related to the drug. Correct callback. Saying that the benefits of the drug outweigh the risks, the company added that the drug lowers blood pressure and reduces the risk of stroke and heart attack. The company advised patients to talk to their doctors about alternative treatment options.

David Light, founder of Valisure, said Wednesday: “It’s been more than three years since the first discoveries of nitrosamine impurities in major drugs and we continue to see ripple effects grow.”

He also noted that his team had discovered benzene, a known carcinogen, in consumer products, including sunscreen and sunscreen. body sprays and the FDA is starting to want the industry to expand even faster. own benzene test.