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According to one study, no data on coronavirus vaccines so far provides reliable evidence to support vaccines for the general population. Review published on Monday By an international group of scientists, including some at the Food and Drug Administration and the World Health Organization.
Among the 18 authors, FDA scientists Dr. Philip Krause and Dr. Featuring Marion Gruber. They announced last month that they would be leaving the agency., at least in part, because they disagreed with the Biden administration’s crackdown on its supporters before federal scientists reviewed the evidence and made recommendations.
Biden administration recommends application of vaccine boosters eight months later first shots. But many scientists opposed the plan, said that vaccines continue to be a strong protector against severe illness and hospitalizations. A committee of FDA advisors, meeting is scheduled To review the data on Friday.
In the new review published in The Lancet, experts said that whatever advantage boosters provide cannot outweigh the benefit of using these doses to protect the billions of unvaccinated people worldwide. Boosters may be beneficial in some people with weakened immune systems, they said, but are not yet necessary for the general population.
Various studies published by the Centers for Disease Control and Prevention, Including three on Fridaysuggests that efficacy against infection with the delta variant decreases slightly over time, while vaccines remain stable against serious diseases in all age groups. Only in older adults over 75 years of age do vaccines show some weakening in protection against hospitalization.
The immunity provided by vaccines is based on protection from both antibodies and immune cells. Although antibody levels may decrease over time, increasing the risk of infection, the body’s memory of the virus is long-lived.
Experts said the vaccines are slightly less effective against infection with the Delta variant than with the Alpha variant, but the virus has yet to evolve to evade sustained responses from immune cells. If a variant emerges that evades the immune response, boosters may be needed even for the general population.
In addition to promoting boosters before they’re needed, experts have warned that any reports of side effects from booster vaccines, such as heart problems or Guillain-Barre syndrome, could undermine confidence in the primary vaccine.
Data from Israel show that booster doses increase protection against infection. But experts said this evidence was only collected a week or so after the third dose, and it may not hold true over time.
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